If guessing is the repairment of thoughts. A patch of some kind. Then does repairment exist in math or physics. Could you connect theories by a guess connection. Here I assume a guess connection is a deterministic procedure to connect different solutions without there being a simple rule for it.
Here I assume the theory of everything resembles machine learning networks with lots of weights or parameters. This way you can get complex behaviour in every circumstance. It would therefor not be so hard to bridge recognized theories.